MOSH/MOAH in infant formula

Levels of MOSH and MOAH in infant formula have been widely discussed in 2020. One of the main issues of the discussion was that not standardised analytical method is available. Consequently, it is up to the laboratories to proof, that they are able to provide reliable results of MOSH and MOAH in infant formula. 

The preparation of a sample of infant formula, which is not only spiked with MOSH and MOAH "on the surface" but with levels of MOSH and MOAH "enclosed" to the material is a challenge. Either a spiked sample or a sample of infant formula, contaminated with MOSH and MOAH is provided in this method ring test.

P2102-MRT is organised as a method ring test. That means, the evaluation is not limited to the pure statistical evaluation of the provided analytical data. Consequently, 

  • all participants are asked to provide the chromatograms of the test sample and the blank sample including the integration of the humps. All chromatograms are published (anonymised with the lab code) in the final report.
  • questionnaire is provided related to the analytical details like internal standards, sample-pretreatment, etc. and related to the confirmation of the results.

The analytical details, which are mentioned above as well as the chromatogramms are summarised in separate parts of the final report. For reasons of fairness, only those participants, which provide details and chromatograms will receive these parts of the report. These data, anonymised and summarised, will help to identify shortcomings, built the basis for further discussion and thus help to enhance the quality of the applied methods.

The analytical results are evaluated with respect to

  • the comparability criterion (z-score), and
  • as far as achievable with respect to the trueness criterion (recovery of the spiked level).


MOSH ≥ n-C10 - ≤ n-C16, MOSH > n-C16 - ≤ n-C20, MOSH > n-C20 - ≤ n-C25, MOSH > n-C25 - ≤ n-C35, MOSH > n-C35 - ≤ n-C40, MOSH > n-C40 - ≤ n-C50, Total MOSH (lower bound), Total MOSH (integration of hump), MOAH ≥ n-C10 - ≤ n-C16, MOAH > n-C16 - ≤ n-C25, MOAH > n-C25 - ≤ n-C35, MOAH > n-C35 - ≤ n-C50, Total MOAH (lower bound), Total MOAH (integration of hump)

Expected time schedule

Please register before:
01 May 2021
Dispatch of samples:
07 June 2021
Deadline for reporting results:
01 July 2021

Costs of P2102-MRT

Ring test and material Amount Price per unit
MOSH/MOAH in infant formula 800 €
Test material infant formula
Infant formula with (spiked) levels of MOSH/MOAH.
100 g included
Blank material
Infant formula, unspiked.
100 g included

Note: PROOF-ACS reserves the right to cancel tests in case of less than ten participants.